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Associate Professor

Bernard LOO

Associate Professor
Programme Leader, SIT BEng (Hons) Pharmaceutical Engineering
PhD, PEng (Chemical & Biomolecular Engineering), Georgia Institute of Technology, Atlanta, Georgia
Cluster:
Food, Chemical and Biotechnology
Email

SIT Appointments

  • Programme Leader, SIT BEng (Hons) Pharmaceutical Engineering
    – Present
  • Associate Professor
    – Present
  • Deputy Cluster Director, Food, Chemical and Biotechnology
    –
  • Programme Director, TUM BSc Chemical Engineering
    –
  • Assistant Professor
    –

Education

  • PhD, PEng (Chemical & Biomolecular Engineering)
    Georgia Institute of Technology, Atlanta , Georgia
  • Bachelor of Chemical Engineering (Chemistry Minor)
    University of Minnesota, Twin Cities ,

Achievements

  • Cell Culture Engineering Travel Award 2012
  • Awarded IA111067 grant, BMRC
  • Awarded JCO exploratory grant, ASTAR Joint Council
  • Sequenced and assembled CHO genome (CHO consortium 2010)
  • Tau Beta Pi Honor Society
  • Awarded Singapore inc. Scholarship 1999

Professional Certification

  • Professional Engineer
    Professional Engineers Board, Singapore

Professional Memberships

  • American Chemical Society Member
  • Institution of Engineers Singapore
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Research Interests

  • CHO genomics engineering
  • Process development of biologics
  • Biological engineering
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Journal Papers

  • Wan Ping Loh, Bernard Loo, Lihan Zhou, Peiqing Zhang, Dong Yup Lee, Yuansheng Yang, Kong Peng Lam. Overexpression of microRNAs enhances recombinant protein production in Chinese hamster ovary cells (2014). DOI: 10.1002/biot.201400050.

  • Franck C. Courtes, Joyce Lin, Hsueh Lee Lim, Sze Wai Ng, Niki S.C. Wong, Geoffrey Koh, Leah Vardy, Miranda G.S. Yap, Dong-Yup Lee, Bernard Loo. Translatome analysis of CHO cells to identify key growth genes. Journal of Biotechnology (2013). DOI:10.1016/j.jbiotec.2013.07.010. Epub 2013 Jul 19

  • Huong Le, Yung-Shyeng Tsao, Nitya Jacob, Ng Sze Wai, Zhong Liu, Anne Kantarjeff, Bernard Loo and Wei-Shou Hu. Transcriptome dynamics of transgene amplification in Chinese Hamster Ovary cells. Biotechnology and Bioengineering (2013) DOI: 10.1002/bit.25117.

  • Vincent Vagenende, Alvin X. Han, Han B. Pek, Bernard L. W. Loo. Quantifying the Molecular Origins of Opposite Solvent Effects on Protein-Protein Interactions. PLoS Comput Biol 9(5): e1003072 (2013).

  • Jeremy Lee, Hui Theng Gan, Sarah Maria Abdul Latiff , Cindy Chuah, Wan Yee Lee, Yuan-Sheng Yang, Bernard Loo, Say Kong Ng, Pete Gagnon. Principles and applications of steric exclusion chromatography. J. of Chromatography A. 1270 (2012) 162– 170.

  • Russell B. Vegh, Kyril M. Solntsev,  Marina K. Kuimova, Soohee Cho, Yue Liang, Bernard L. W. Loo, Laren M. Tolberta and Andreas S. Bommarius. Reactive oxygen species in photochemistry of the red fluorescent protein "Killer Red". ChemComm (2011).

  • Nitya M Jacob, Wei-Shou Hu, Bernard Liat Wen Loo, Miranda Yap. Using Genomic Tools to Improve the Production of Biologics. Chemical Engineering Progress (2009).

  • Bernard L.W. Loo, Anshul Dubey, Realf MJ, Jay H. Lee and Andreas S. Bommarius. Identifying interacting residues using Boolean Learning and Support Vector Machines: case study on mRFP and DsRed proteins. Biotech J 3(1): 63-73. (2008).

  • Bernard L.W. Loo, Javier F. Chaparro-Riggers,  Karen M. Polizzi, Phillip R. Gibbs, Xiao-Song Tang, Mark J. Nelson, and Andreas S. Bommarius. Revealing biases inherent in recombination protocols. BMC Biotech  7:77. (2007).  

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