Joy PANG
Profile
SIT Appointments
- Associate Professor– Present
- Assistant Professor–
- Lecturer–
Education
- PhD (Biochemistry)University of Illinois, Urbana-Champaign , United States
- BSc (Microbiology)University of California, San Diego , United States
Achievements
- MITx Postdoctoral Teaching Fellow–
- Howard Hughes Summer Research Fellow–
Corporate Experience
- Research Associate, GenWay Biotech Inc, San Diego, CA, USA–
Research
Research Interests
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Protein chemistry
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Synthetic biology
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Bioanalytics
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Genomics
Publication
Journal Papers
Keegan, C., Krutzik, S., Schenk, M., Scumpia, P. O., Lu, J., Pang, Y.L.J., Russell, B.S., Lim, K.S., Shell, S., Prestwich, E., Su, D., Elashoff, D., Hershberg, R.M., Bloom, B.R., Belisle, J.T., Fortune, S., Dedon, P.C., Pellegrini, M., and Modlin, R.L. (2018) Mycobacterium tuberculosis Transfer RNA Induces IL-12p70 via Synergistic Activation of Pattern Recognition Receptors within a Cell Network, Journal of Immunology, doi: 10.4049/jimmunol.1701733
Hia, F., Chionh, Y. H., Pang, Y. L. J., DeMott, M. S., McBee, M.E., and Dedon, P. C. (2015) High fidelity isolation of RNA from mycobacteria: A new approach optimized for quantitative and chemical analyses of non-coding RNA species, Nucleic acids research, 43, e32.
Cai, W. M., Chionh, Y. H., Hai, F., Gu, C., Kellner, S., McBee, M. E., Ng, C. S., Pang, Y. L. J., Prestwich, E. G., Lim, K. S., Indrakanti, R. B., Begley, T. J., Dedon, P. C. (2015) A platform for discovery and quantification of modified ribonucleosides in RNA: Application to stress-induced reprogramming of tRNA modifications. Methods enzymology, 560, 29-71
Hia, F., Chionh, Y. H., Pang, Y. L. J., DeMott, M. S., McBee, M.E., and Dedon, P. C. (2015) High fidelity isolation of RNA from mycobacteria: A new approach optimized for quantitative and chemical analyses of non-coding RNA species, Nucleic acids research, 43, e32.
Pang, Y. L. J., Abo, R., Levine, S. S., and Dedon, P. C. (2014) tRNA-seq for quantifying changes in tRNA copy number: Diverse cell stresses induce unique patterns of tRNA up- and down-regulation, Nucleic acids research, 42, e170.
Pang, Y. L. J., Poruri, K., and Martinis, S. A. (2014) tRNA synthetase – tRNA aminoacylation and beyond, Wiley Interdisciplinary Reviews. RNA, 5, 461-480.
Chionh, Y. H., Ho, C-H., Pruksakorn, D., Babu, R. I., Ng, C. S., Hia, F., McBee, M. E., Su, D., Pang, Y. L. J.,Gu, C., Dong, H., Prestwich, E., Shi, P-Y., Preiser, P., Alonso, S., and Dedon, P. C. (2013) A multidimensional platform for the purification of non-coding RNA species, Nucleic Acids Research, 41, e168.
Chan, C. T., Pang, Y. L. J., Deng, W., Babu, I. R., Dyavaiah, M., Begley, T. J., and Dedon, P. C. (2012) Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins, Nat Commun 3, 937
Anderson, M., Huh, J.H., Ngo, T., Lee, A., Hernandez, G., Pang, Y. L. J., Perkins, J., Dutnall, R.N. (2010) Co-expression as a convenient method for the production and purification of core histones in bacteria, Protein Expr Purif 72(2), 194-204
Pang, Y. L. J. and Martinis, S. A. (2009) A paradigm shift for the amino acid editing mechanism of human cytoplasmic leucyl-tRNA synthetase, Biochemistry 48, 8958-64.
Nawaz, M. H., Pang, Y. L. J., and Martinis, S. A. (2007) Molecular and functional dissection of a putative RNA-binding region in yeast mitochondrial leucyl-tRNA synthetase, J Mol Biol 367, 384-394.
Martinis, S. A., and Pang, Y. L. J. (2007) Jekyll & Hyde: evolution of a superfamily, Chem Biol 14, 1307-1308.