John
Soo Yang
Goh
Profile
Education
- PhD in BiochemistryNational University of Singapore , Singapore
- Bachelor of Engineering in ChemNational University of Singapore , Singapore
Applied Research
Technical Skills
- Cell Line Engineering
- Recombinant Protein Expression and Analysis
- Molecular Diagnostics
Current Projects
- An optimised workflow for a lab-developed Micro RnA based Liquid biopsy test kit for Lung Cancer Diagnosis– Present
Teaching
Teaching Modules
Chemical Engineering, BEng (Hons)
- CHE2015 - Engineering Practice
Pharmaceutical Engineering, BEng (Hons)
- PHE3013 - Bioseparations Laboratory
- PHE3018 - Unit Operations Laboratory
- PHE3232 - Bioprocess Engineering
- PHE3233 - Cell Culture Laboratory
- PHE4012 - Plant Design and Operations
- PHE2224 - Organic Chemistry Laboratory
Publications
Journal Papers
Goh JS, Chan KF, Song Z. Production of highly sialylated recombinant glycoproteins using ricinus communis agglutinin-I-resistant CHO Glycosylation Mutants. Methods Mol Biol. 2015. 1321, 323-33
Goh JS, Liu Y, Liu H, Chan KF, Wan C, Teo G, Zhou X, Xie F, Zhang P, Zhang Y, Song Z. Highly sialylated recombinant human erythropoietin production in large-scale perfusion bioreactor utilizing CHO-gmt4 (JW152) with restored GnT I function. Biotechnol J. 2014. 9, 100-9.
Goh JS, Liu Y, Chan KF, Wan C, Teo G, Zhang P, Zhang Y, Song Z. Producing recombinant therapeutic glycoproteins with enhanced sialylation using CHO-gmt4 glycosylation mutant cells. Bioengineered. 2014. 5, 269–73.
Zhang P, Haryadi R, Chan KF, Teo G, Goh J, Pereira NA, Feng H, Song Z. Identification of functional elements of the GDP-fucose transporter SLC35C1 using a novel Chinese hamster ovary mutant. Glycobiology. 2012. 22(7), 897-911.
Wong DC, Wong NS, Goh JS, May LM, Yap MG. Profiling of N-glycosylation gene expression in CHO cell fed-batch cultures. Biotechnol Bioeng. 2010. 15,107(3), 516-28.
Goh JS, Zhang P, Chan KF, Lee MM, Lim SF, Song Z. RCA-I-resistant CHO mutant cells have dysfunctional GnT I and expression of normal GnT I in these mutants enhances sialylation of recombinant erythropoietin. Metab Eng. 2010. 12, 360-8.